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Anatomy and Physiology of Eyelashes!

Human have 90 to 160 eyelashes in the upper eyelid and 75 to 80 in the lower eyelid, with great variation of length. The lashes typically originate from the anterior lamella of the eyelid where they lie on the tarsal plate. Each human eyelash lives an average of 3 to 6 months. The growth phase (anagen) of the eyelash hair follicle and eyelash lasts for approximately 30 days. At the end of the eyelash growth period, a brief transition stage (catagen) of 15 days follows, with shortening of the hair follicle. Finally, the follicle enters a resting phase (telogen) of about 100 days, leading to the detachment of the eyelash. The length of an eyelash can vary greatly, from 8 to 12 mm in the upper lid and from 6 to 8 mm in the lower lid, and depends on the ethnicity of the individual. Eyelash follicle growth rate is also quite variable, with an average of 0.12 to 0.14 mm daily. All eyelashes are characterized by a tendency to bend from the bulb to the top of the shaft.

Beyond their aesthetic and social functions, eyelashes serve a protective function by defending the eye against debris and triggering the blink reflex.

Prostamides metabolism